Expert Video - What are the main prescription medicines for opioid-induced constipation (OIC)?

Gastroenterologist Dr. Jeanetta Frye, an expert on chronic constipation, discusses the main prescription medications available to treat opioid-induced constipation (OIC).  These medications include lubiprostone, methylnaltrexone bromide, naloxegol and naldemidine. Dr. Frye explains how each one works to help relieve OIC, such as by blocking the effects of opioid medications in the digestive system.

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This educational activity has been developed by the International Foundation for Gastrointestinal Disorders and Mechanisms in Medicine Inc.

This activity is supported by independent educational grants from AbbVie, Ironwood Pharmaceuticals and Takeda.

This website is part of the Animated Patient® series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.